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Moreover, LNA043 is currently being investigated in clinical trials for the treatment of articular cartilage lesions (NCT03275064) and knee osteoarthritis (NCT04864392, NCT04814368)

J Vet Pharmacol Ther

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At present, our team has not yet conducted research on the polarization of microglia, which will be the next research goal of our team to explore the pathway how to regulate the polarization of microglia by Sirt1 agonist or antagonist in vivo and in vivo respectively
