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In East Africa, SSG remains a primary treatment, though resistance has been reported, prompting the use of SSG-paromomycin combinations

In mouse models of type 2 diabetes induced by a highfat diet and streptozotocin, 4 weeks of 5amino1mq injection reduced fasting blood glucose by 25%30%, increased insulin secretion by over 20%, and significantly decreased cell apoptosis

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A promising target Mcl-1 belongs to a family of five proteins that play roles in controlling programmed cell death, or apoptosis