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Finally, it was validated by animal models

Similarly, activation of the optogenetic chloride pump halorhodopsin induces neuronal hyperpolarization, which secondarily drives potassium ions into cells, lowering extracellular potassium concentration and indirectly inhibiting neighboring non-expressing neurons, demonstrating a network-wide inhibitory effect (Parrish et al., 2023)

They went because of the check

10.15761/jsin.1000172 J
These changes increase the risk of infertility, subfertility, and chromosomal aberrancies in sperm
