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The formation of m + 4/5 -KG occurs through condensation of m + 2 acetyl-CoA with m + 2/3 oxaloacetate and requires completion of two TCA cycles

Here, we present evidence that latent EBV triggered lipid ROS production in newly infected primary human B-cells, which induced vulnerability to ferroptosis inducing agents at multiple times post-infection (Fig

10.1126/science.1249361 279 NewtonK.StrasserA.KayagakiN.DixitV