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Although primarily regarded as a gas-exchange organ, the lung demonstrates remarkable metabolic activity, continuously enduring high oxidative stress and substantial circulatory demands

3 The onset and development of cuproptosis 3.1 Cuproptosis Recently, a novel form of copper-dependent cell death, reliant on mitochondrial respiration, has been identified and termed cuproptosis (Tsvetkov et al., 2022)
Conclusion Vitamin C shows good results as an antibacterial and anti-biofilm agent in vitro and in vivo alone or combined with antibiotics

As both bevacizumab and TMZ damage mitochondria (155), these drugs will contribute further to tumor cell reliance on fermentation metabolism thus increasing microenvironment acidification ( Figure 3A )

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