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In dogs, supplementation has been associated with improved exercise performance and recovery in certain contexts, likely by supporting energy availability during activity
Coggan AR, Broadstreet SR, Mahmood K
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Furthermore, the HIF-1 gene plays a critical role in glutamine metabolism in tumors by stimulating the expression of SLC7A11, promoting the exchange of glutamine and cystine, increasing glutathione levels within tumor cells, and preventing the accumulation of ROS [151]
