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GOT2 catalyzes the conversion of oxaloacetate to aspartate in the mitochondria and has been shown to be an important regulator of cancer metabolism (13)

The activity of several protein kinases, and particularly of protein kinase C (PKC) sub-family members can be modulated in human neuronal cells supplemented with tocopherols and tocotrienols (Galli et al., 2017)

To understand if hypoxia could be a stimulus for mitophagy, we quantified mitolysosomes after acute OHT, finding significantly greater mitolysosome number in cells positive for pimonidazole, an adduct formed in cells exposed to hypoxia

When the body is less burdened by toxins, skin health and radiance is a natural byproduct

doi: 10.1016/j.neuropharm.2019.05.010, PMID: [DOI] [PubMed] [Google Scholar] 116.de Bartolomeis A, De Simone G, De Prisco M, Barone A, Napoli R, Beguinot F, et al