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Within these reactive species we find superoxide anion (O 2 ), hydroxyl radical ( OH), nitric oxide (NO ), as well as other species of non-free radicals such as hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HClO) and peroxynitrite (ONOO )
This suggests that the activity of MRP proteins will be stimulated in response to stress-induced increases in cytosolic GSSG accumulation and function to dampen such increases
Free Radic Biol Med 1992, 12:337345
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