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: Prevention of cisplatin-induced hearing-loss by sodium thiosulfate in medulloblastoma

Chem Biodivers 4 , 17701804, (2007)

As indicated below, different combinations of the M and H subunits generate LDH isoforms in different tissues

When the ability of tumor cells to metabolize Gln is significantly greater than that of CD8+ T cells, the tumor-killing ability of the CD8+ T cell subgroup is inhibited

In dogs with phenobarbital-associated toxicosis, clinical, biochemical, and histologic improvement can occur if the drug is discontinued or used at a reduced dosage prior to severe, end-stage liver disease
