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Systemic and endemic mycoses are caused by dimorphic fungi belonging to species of the genus Histoplasma, Paracoccidioides, Coccidioides, Blastomyces, Talaromyces and Emergomyces

As the NAC samples of interest were from a DMEM solution, it was important that the matrices present (amino acids, water soluble vitamins, sodium pyruvate, HEPES, glucose, minerals, sodium carbonate, sodium bicarbonate, salts, etc.) in those samples did not interfere with the NAC quantitation

In the development of liver fibrosis and cirrhosis, amino acid metabolic reprogramming plays multiple key roles, which not only participates in the systemic energy adaptation of the disease state, but also directly regulates the progression and reversal of fibrosis through specific mechanisms [125]

doi: 10.1159/000363162