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In human cells, PGRMC1 deletion reduces CYP51A1 enzymatic activity, thereby suppressing cholesterol biosynthesis and promoting the accumulation of toxic sterol intermediates

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Plant Cell Physiol 34:12591266 Kumar S, Kaur A, Chattopadhyay B, Bachhawat AK (2015) Defining the cytosolic pathway of glutathione degradation in Arabidopsis thaliana : role of the ChaC/GCG family of gamma-glutamyl cyclotransferases as glutathione-degrading enzymes and AtLAP1 as the Cys-Gly peptidase
