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Animal studies spanning over 20 years show gastric ulcer healing, tendon repair, muscle regeneration, and neuroprotection with minimal toxicity, even at doses 10 to 100 times the therapeutic range (Sikiric et al., Curr Pharm Des 2018)

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used liver biopsy to compare the liver cell status and Nrf2-mediated antioxidant protein of 13 PBC patients before and after UDCA treatment and collected serological samples for analysis such as serum total bilirubin, alkaline phosphate Enzymes and other indicators

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