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Behringer RR, Lewin TM, Quaife CJ, Palmiter RD, Brinster RL, DErcole AJ: Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice

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The stability of a protein disulfide bond is determined by its intrinsic stability, K eq , plus the ratio of the concentrations of GSH and GSSG: Only very stable protein disulfide bonds, with large values of K eq , could be populated in the cytosol

In addition, FcRn mediates transcytosis of IgG across mucosal epithelial barriers and the human placenta 18,19,20

Activated CAFs overproduce and cross-link extracellular matrix (ECM) components, creating a fibrotic constraint that physically blocks T-cell movement [154]