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Accumulation of intracellular lipid peroxides without timely elimination can cause oxidative damage to DNA, proteins, and the cell membrane ultimately leading to ferroptosis

[DOI] [PubMed] [Google Scholar] 167.Volterra A., Trotti D., Floridi S., Racagni G

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Its most critical roles include supporting the production of healthy red blood cells, DNA synthesis, strengthening the brain and nervous system, and enhancing immune function

The diverse biological roles of melatonin in neurodegenerative diseases are summarized in Table 1, which outlines its impact on molecular pathways, cellular structures, and physiological processes across both experimental and clinical models