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Collectively, modulating the IVD microenvironment, growth factor signaling, and specific intracellular pathways represents a potential strategy to enhance NPPC function and promote endogenous repair in degenerative disc disease (Fig
Association of the dioxin receptor with the M r 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor
It was reported that Klotho restrained IGF signalling, which protected against renal hypertrophy in diabetic mice or cystic expansion in mice with polycystic kidney disease 33,34
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Day NE (1996)
