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High salt concentration might either interfere with intermolecular electrostatic interactions between aptamer and target protein or cause structural disruption of aptamer resulting in destabilization of aptamer-target protein bond 33
McMenamy RH, Lund CC & Wallach DF (1960) Unbound amino acid concentrations in plasma, erythrocytes, leukocytes and urine of patients with leukemia
The treatment and management of MS have primarily been dependent on immune-based therapies, including immune modulation, immune suppression, and immune cell sequestration
Blockage by earwax can occur at any age and accounts for many cases of apparent hearing loss
doi: 10.1016/S2468-1253(19)30409-1
