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It is characterized by reduced BMD and compromised bone microarchitecture, ultimately leading to increased skeletal fragility and a higher incidence of fragility fractures (Mizoguchi and Ono, 2021
This largely limits the efficacy of the drugs and the survival of the patients
Illustratively, these prime lesions, both peripheral and central, were also ameliorated
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Its important to note that the benefits of growth hormone therapy are most prominent in individuals with confirmed growth hormone deficiencies or certain medical conditions