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Rat amylin analogs with these affinity-enhancing mutations also significantly enhanced potency for calcitonin receptor activation by 5- to 11-fold compared to endogenous rat amylin and a clinical drug pramlintide (Figure 9D and Table 3)

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PubMed Duzel, A., Vlainic, J., Antunovic, M., Malekinusic, D., Vrdoljak, B., Samara, M., Gojkovic, S., Krezic, I., Vidovic, T., Bilic, Z., Sjekavica, I., Djuzel, A.R., Knezevic, M., Sever, A.Z., Lojo, N., Kokot, A., Sever, M., Drmic, D., Seiwerth, S., & Sikiric, P

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