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Because B12 is water-soluble, excess amounts are safely excreted by the body

Hence to ensure accurate measurements, it is important to separate the blood samples and freeze the serum as soon as possible after collection

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Other effects require reporting to a medical team as soon as possible, including: An allergic reaction, including rashes, itching, hives, and a swollen face, tongue, throat, or lips High blood sugar symptoms Other liver damage symptoms, including pain in the upper-right abdomen, appetite loss, dark yellow urine, a yellow tint in the skin or eyes known as jaundice, and feeling unusually weak or tired Tingly, numb, or painful feet Following a balanced diet means that most people are unlikely to develop a B vitamin deficiency