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First, isolate newly identified microbial metabolites that modulate systemic FTN homeostasis, establish their molecular targets and signaling cascades in intestinal epithelial cellsin particular, how they interact with the dimerization of HIF-2/ARNT

Intraneuronal absorption requires axonal transport and thus occurs over hours to days to reach target tissue throughout the brain

Developed by Novo Nordisk and characterized by Raun et al

Some ITCs demonstrate a hormetic effect, offering cytoprotective benefits at low doses and cytotoxic, antitumor properties at higher doses (149, 150)

cDNA was used for RT-PCR or real-time PCR assay