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Furthermore, long-term moderate-intensity exercise can upregulate the expression of mitochondrial inner membrane uncoupling protein 2 (UCP2) via the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1a)/PPAR pathway, thereby reducing endoplasmic reticulum stress and lowering intracellular ROS levels (Zhou et al., 2016)

Thus, the extensive chemical rearrangement justifies the spectrophotometric changes of hemin by thiols, and iron appears to be necessary for the completion of the reaction

Pawlak, R., et al

10.1016/j.jaci.2015.07.034 44

This antioxidant protects the liver from free radicals, which are harmful chemicals that can cause damage
