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Roxadustat (FG-4592), an inhibitor of prolyl hydroxylase of hypoxia-inducible factor (HIF), mitigates folic acid-induced kidney fibrosis via the Akt/GSK-3/Nrf2 pathway [193]

Documented literature suggests a redox imbalance in smokers which may be an important factor in mediating tissue damage in several tissues and that antioxidants are effective in overcoming the oxidative stress-inducing effects of nicotine 42,43,44

Enantiomer-specific pharmacokinetics of D,L-3-hydroxybutyrate: implications for the treatment of multiple acyl-CoA dehydrogenase deficiency

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