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J Dermatol (2024) 51:10225

Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]
Dos Santos RB, Lakkadwala S, Kanekiyo T, Singh J (2019) Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties

PubMed , doi:10.1152/ajplung.00348.2006

eIF2 must not be confused with EIF2A, which also participates in translation initiation, albeit only for specific mRNAs in a codon-dependent manner
