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Similar content being viewed by others Introduction Aging is associated with cognitive decline and increased vulnerability to Alzheimers disease (AD), the leading cause of dementia, accounting for 6080% of cases [1]

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The pMET protein levels peak at P7P14 in the neocortex, a period corresponding to synaptogenesis and dendritic outgrowth, and are downregulated during the 3rd post-natal week, between P14 and P17, when pruning and functional synapse maturation occur (Eagleson et al., 2016)