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This statement is further supported by other epidemiological studies showing the important role of psychosocial stress, such as depression, social isolation, distress, or trauma in the more rapid progression [14, 165] and development [166, 167] of various tumours

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[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Woo H.A., Yim S.H., Shin D.H., Kang D., Yu D.Y., Rhee S.G

The lack of B12 halts the methylation cycle, which leads to a buildup of toxic homocysteine