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19 However, tumor cells also utilize GST to form a GSHX complex between antitumor drugs and GSH, proceeding to excrete the complex out of the cell by Pgp and MRP
Although the exact mechanism of its action needs more exploration, within hepatocytes it removes Cu bound to proteins and binds it in stable complexes which are cleared into bile (85)

Footnotes Competing interests: None declared

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[DOI] [PubMed] [Google Scholar] [131].Xie Y, Hou W, Song X, et al