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Microbial Conversion of Choline to Trimethylamine Requires a Glycyl Radical Enzyme
Since melatonin is mainly metabolized by cytochrome P450 (CYP) 1A2 and CYP2C19, inhibitors of these enzymes lead to higher concentration of melatonin in the body [42]

Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

doi: 10.1186/s12891-017-1641-y