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Description
Experiments have shown that overexpression of BECN1 significantly increases levels of malondialdehyde (MDA), Fe 2+ , and ROS in cells, promoting the occurrence of ferroptosis induced by CaOx crystals
This is suggested to lead to the accumulation of superoxide and hydroxylic radicals in a cell
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Overall/Objective response rates (ORRs) among patients with EGFR mutation-positive cancer cells receiving gefitinib have been documented to range from 62 to 85% [7,8,9,10]
Turtoi, A
