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Furthermore, certain medications, like proton pump inhibitors for acid reflux, metformin for diabetes, and some medications for peptic ulcers or heartburn, can impair your bodys ability to process Vitamin B12

In fact, many veterinarians will give cats who have chronic GI symptoms a shot of cobalamin at the beginning of therapy, before the results of cobalamin testing are in and a definitive diagnosis has been made, because it is so safe and might make the cat feel better faster

Environmental factors like UV exposure or pollution accelerate this by inducing more DNA damage, thus more PARP activity

Annals of Internal Medicine