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People under high stress or with digestive issues that impair nutrient absorption

I honestly did not see much of a difference between the couple weeks that I did not take them because I could inject myself versus the times when Im on them

Megaloblastic anemia could produce oxygen-deprived organs and tissues, numbness in the hands and feet, depression, confusion, dementia, and heart failure

10.1126/science.3798107

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision
