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Eder LN, et al

By binding to CD80 and CD86 receptors on APC and obstructing the costimulatory effects of the T cell surface molecule CD28, activation of CD8 + T cells and the release of inflammatory cytokines linked to AA, namely IL2, TNF, and IFN, are both efficiently inhibited by abatacept [226]

(2021) 118:e2009620118

OCT-4, NANOG and SOX-2 contribute to the hallmark characteristics of stem and putative cancer stem cells by activation of target genes that encode pluripotency and self-renewal mechanisms 57

[DOI] [PMC free article] [PubMed] [Google Scholar] Seiner D