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Patients should inform their prescribing physician about all supplements, including creatine, to ensure comprehensive monitoring and personalized recommendations
Notably, mitochondrial fusion typically correlates with anti-inflammatory M2 macrophage polarization [51, 52], while excessive fission promotes pro-inflammatory M1 polarization [53]
Conversely, mechanistic studies must further explore the intersection of NAD + intersects with bile acid metabolism, cholesterol homeostasis, and the gut-liver axis, as these areas that remain insufficiently characterized
Ecology 46 (1), 117132
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