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Due to the already sensitive nature of dopaminergic neurons to redox imbalance and ROS generation, the additional reduction of an antioxidant like GSH causes neuron loss (Smeyne and Smeyne, 2013)

and a detailed description of the cases is shown in Table 8

The improvement of the electric shock-like sensations with gabapentin 300 mg daily reinforces the neuropathic nature of her symptoms, which aligns with both vitamin B12 deficiency and fibromyalgia as underlying causes [35]

J Mol Neurosci 20:349-356

METTL3 and ALKBH5 oppositely regulate m(6)A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes