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10.1016/j.bbamcr.2012.06.019 Biochim Biophys Acta

It supports metabolic processes and plays a crucial role in various systems, including digestion, cognitive function, mental clarity, aging, and overall energy levels

The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history

This is first clinical study demonstrating that a TfR antibody can deliver the enzyme IDS across the BBB into the brain for treatment of Hunter syndrome (mucopolysaccharidosis type II)

This activation leads to the phosphorylation of IB, which is then ubiquitinated and degraded by the proteasome