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You might consider a B12 shot if you follow a vegetarian or vegan diet, since B12 comes mainly from animal foods

Formulation alternatives may provide relief: Different tablet formulations with alternative inactive ingredients may be better tolerated Liquid preparations can be easier to tolerate and allow flexible dosing Intramuscular injections completely avoid the gastrointestinal tract and are particularly useful for those with absorption issues (such as pernicious anaemia or malabsorption) or persistent oral intolerance Review inactive ingredients: Examine the supplement label for potential irritants or allergens

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Calculating your injection volume Once you know your target dose for the week, you need to convert milligrams to syringe units based on your reconstitution concentration