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Certain factors, such as dietary restrictions, digestive issues, or age-related changes, can impact B-12 absorption, making supplementation a beneficial option for many individuals.

145 A complicating factor in determining metformin-induced deficiencies is that there are large vitamin B12 stores in the liver and these can take up to five years to manifest as a deficiency

5-MTHF This is the methylated, active form of folic acid that is needed for protein metabolism, RNA and DNA repair, and red blood cell formation

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a key role in energy production, red blood cell formation, and neurological function

Vitamin B12 Replacement Therapy The main treatment for pernicious anemia is vitamin B12 replacement therapy