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I cover its natural role in plasma and tissues, how levels fall with age, and the surprising breadth of its actionsfrom extracellular matrix remodeling and antioxidant effects to cognitive protection, cardiovascular benefits, and boosted wound healing

40,41 Additional risk factors include sexually transmitted infections such as gonorrhea or chlamydia, which produce genital inflammation that can weaken mucosal barriers that would normally help shield the body from infection

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Progerin was known responsible for many cellular defects, one of which is the attrition of mesenchymal stem cells (MSCs) that leads to tissue defect [116]