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Nutrition 24:305313 Malaguarnera M, Vacante M, Bertino G, Neri S, Malaguarnera M, Gargante MP, Motta M, Lupo L, Chisari G, Bruno CM, Pennisi G, Bella R (2011) The supplementation of acetyl-l-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon- 2b plus ribavirin

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For example, during nutrient deprivation or increased energy demand, signaling pathways such as the AMP-activated protein kinase (AMPK) pathway may induce phosphorylation, enhancing the enzyme's activity to promote fatty acid oxidation