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INTRODUCTION Multiple myeloma (MM) is the second most common hematologic malignancy worldwide, characterized by malignant plasma cells (mPC) accumulating in the bone marrow (BM)

Doses above ~500 mcg/day are not generally linked to added benefit in the reference literature, and none of this reflects proven human efficacy

Numerous patients exhibit a deficiency in vitamin B12 due to factors such as stress, poor dietary habits, subpar digestion, or the depletion of this crucial nutrient by certain medications