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Aif3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis

G.ChoppM

This Trametes versicolor is commonly widespread across Ireland and Britain and this Turkey tail fungus occurs all over the mainland of Europe from northern Scandinavia right down to the Mediterranean region., This wood-rooting fungus is also found in Asia and North America

Studied extensively in rodent models for its role in supporting angiogenesis , tendon and ligament healing , gut barrier repair , and inflammatory regulation

We showed that extra-mitochondrial WT PINK1 inhibit tyrosine hydroxylase (TH) and down regulate DA level in DA neurons, whereas pathogenic PINK1 mutations up-regulate TH activity and DA content in DA neurons