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Typical use accounts for missing a pill or two, being a bit late with a new pack, or some other incident that prevents someone from taking the pill every day at the same time

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Any tightness in the muscles around the hip and knee or restricted motion in the hip joint itself can affect the biomechanics of the trunk and lower limb, including the tension in the piriformis muscle, so this will need to be addressed

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Published studies have examined its effects in rodent models across multiple organ systems