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Furthermore, glutathione acts as an essential electron donor for specific antioxidant enzymes within the mitochondria, most notably Glutathione Peroxidase (GPx)

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Dismutation of O 2 (either spontaneously or, at a significantly faster rate, through a reaction catalyzed by MPO itself [90]) gives rise to oxygen and H 2 O 2 , the latter being a precursor of one of the most powerful naturally occurring oxidants, the hydroxyl radical (OH)

Neuville, F.-M

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