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Current management guidelines include the recommendation that patients treated with pegylated interferon alpha (peginterferon) and ribavirin have therapy stopped if HCV RNA is still present after 24 weeks of treatment

Gesellchen et al., 2005)

Ludwig H, Durie BG, McCarthy P, Palumbo A, San Miguel J, Barlogie B, Morgan G, Sonneveld P, Spencer A, Andersen KC, Facon T, Stewart KA, Einsele H, Mateos MV, Wijermans P, Waage A, Beksac M, Richardson PG, Hulin C, Niesvizky R, Lokhorst H, Landgren O, Bergsagel PL, Orlowski R, Hinke A, Cavo M, Attal M

During the Maillard reaction stage, highly reactive carbonyl compounds are formed, including glyoxal, methylglyoxal, or 3-deoxyglucosone (Wells-Knecht et al., 1995

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