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Brain Topogr 36(5):736

Preliminary activity of AMN107, a novel potent oral selective Bcr-Abl tyrosine kinase inhibitor, in newly diagnosed Philadelphia chromosome (Ph)-positive chronic phase chronic myelogenous leukemia

By enhancing the binding affinity, improving bioavailability, ensuring biocompatibility, and enabling controlled drug release, personalized nanomedicine maximizes therapeutic efficacy while delivering the drug to the intended target at the optimal time for each patient

The various NAC administration schemes could protect hair cells (as shown by distortion product otoacoustic emissions) or neural fibers (as shown by auditory brainstem responses), but no scheme provided full recovery of cochlear function and neural fibers, at seven days post exposure