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Chronic alcohol abuse through oxidative reduction response and inflammatory activation leads to cytoskeletal destabilization of BBB integrity, which further activates astrocytes and thus finally causes BBB disruption and neuronal death [68]
doi: 10.1016/j.expneurol.2009.08.014
Catalase exhibits antifungal effects primarily by producing reactive oxygen species (ROS) and breaking down hydrogen peroxide (Figure 5)
Given the absence of demonstrated abnormalities in fibril morphology or collagen synthesis, this mechanism may be the most plausible
