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10.1016/j.mrgentox.2014.04.006 5 AllamehA.Niayesh-MehrR.AliarabA.SebastianiG.PantopoulosK

In a large cohort of healthy women attempting conception ( n = 1209 cycles), higher urinary isoflavones were not associated with meaningful changes in cycle length but were linked to lower odds of menstrual irregularity (OR 0.79, 95% CI 0.640.98), whereas higher lignan excretion showed slightly increased irregularity risk (OR 1.32, 95% CI 1.061.64) [163]

doi: 10.3389/fimmu.2024.1346656 Received 29 November 2023 Accepted 29 January 2024 Published 20 February 2024 Volume 15 - 2024 Edited by Saikolappan Sankaralingam, AIM Laboratories, United States Reviewed by Nicoletta Sorvillo, Takeda Development Centers Americas, United States Updates Copyright 2024 Kannan and Girija A.S

The release medium was phosphate-buffered saline, prepared according to pharmacopeial standards and consisting of 0.02% KCl (w/v), 0.02% KH 2 PO 4 (w/v), 0.116% Na 2 HPO 4 (w/v), and 0.8% NaCl (w/v) (adjusted with 10 mM NaOH, pH 7.4) ( The CUR was formulated in a 2% polysorbate 80 aqueous solution, achieving a final concentration of 0.6 mg/mL