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Studies like that could damage the reputation of cryosurgery, wrote one physician, who also complained that the ten-second application of liquid nitrogen used in the study was too short, so it was an unfair comparison

Additionally, carnosine was often administered in combination formulations, making it difficult to isolate its individual effects

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For instance, neurons with longer axons and multiple synapses require more energy for axonal transport or long-term plasticity (Salehi et al., 2019c

Cells generate localized ROS near the nuclear envelope (NOX isoforms), the outer mitochondrial membrane (MAO facing the cytosol) and cytosolic dehydrogenase complexes adjoining the nucleus (Kaludercic et al