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Increased cytokine surge also leads to elevated oxidative stress and DNA damage, which could then cause HCC initiation [170]
163 The effect of curcumin on the oral bioavailability of sulfasalazine was investigated in eight healthy human subjects, who showed remarkably increased plasma concentrations of sulfasalazine and reduced expression of breast cancer resistance protein (BCRP)
doi: 10.1016/j.biopha.2018.12.077 52 Frontin-RubioJSantiago-MoraRMNieva-VelascoCMFerrnGMartnez-GonzlezAGmezMVet al
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