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In short, as an important antioxidant enzyme in mammals, GPX4s role in the oxidative stress response cannot be ignored

HISTORICAL OVERVIEW In 1888 de Rey-Pailhade discovered that yeast cells contain a substance that he named philothion, which reacts spontaneously with elemental sulfur to give hydrogen sulfide (reviewed by Meister, 1988a)

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A single daily injection will not work

However, the definitive involvement of these MAPK and G i/o -coupled pathways in regulating proliferation has not been established (indicated by dashed lines)