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Deferoxamine is the first one

Thus, NRF2 supports nucleotide biosynthesis through direct transcriptional mechanisms and by rewiring cellular metabolism to funnel metabolic intermediates into the pathways

Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

Mitochondrion 43:115

It also heightens the risk of several cancers, including colorectal, post-menopausal breast, uterine, esophageal, kidney and pancreatic cancers (WHO 2024
